Effect of Radiotherapy on Painful Bone Metastases

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Stereotactic body radiotherapy in the management of painful bone metastases.

More than 100,000 new cases of bone metastases are diagnosed each year, and they present an important clinical problem. They cause significant morbidity and quality-of-life issues in cancer patients. Conventional external-beam radiotherapy is currently the most common method to treat these metastases, with several randomized controlled trials showing no difference in effectiveness between multi...

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Radiotherapy in palliative treatment of painful bone metastases

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Bone Metastases Radiotherapy

Despite high-level evidence in the literature, the use of single-fraction radiotherapy (RT) for management of painful bone metastases is not widely practiced in the world, as highlighted in several practice-pattern surveys. Fractionation of palliative RT for bone metastases has not been addressed in Iran, where the most common clinical practice is the use of 30 Gy in 10 fractions. Thus, we deci...

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[Re-irradiation of painful bone metastases].

Little is known about what the best treatment is for patients returning with painful bone metastases after their first radiotherapy. Treatment should be individualized and should depend on the histology of the primary tumour, the general condition of the patient, systemic treatment options and prognosis. The precise effect of re-irradiation of painful bone metastases has scarcely been studied. ...

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Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases.

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ژورنال

عنوان ژورنال: JAMA Oncology

سال: 2017

ISSN: 2374-2437

DOI: 10.1001/jamaoncol.2016.6770